INT235390

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (BGLAP) cytoplasm (BGLAP) signal transducer activity (HTR1A)
extracellular space (BGLAP) extracellular region (BGLAP) structural molecule activity (BGLAP)
HTR1A (Homo sapiens)
BGLAP (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 15 100.00 Very High Very High Very High
antagonist 4 95.12 Very High Very High Very High
5HT 141 87.96 High High
antidepressant 19 86.00 High High
Sumatriptan 5 86.00 High High
depression 1 49.76 Quite Low
Dopamine 14 5.00 Very Low Very Low Very Low
Kinase C 13 5.00 Very Low Very Low Very Low
Raphe 9 5.00 Very Low Very Low Very Low
amygdala 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 89 86.84 High High
Depression 1 49.76 Quite Low
Congenital Anomalies 7 5.00 Very Low Very Low Very Low
Obsessive-compulsive Disorder 6 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Tics 1 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, MK-212, which demonstrates an affinity for 5HT1A and 5HT2C receptor subtypes, and the 5HT1A receptor agonists ipsapirone or buspirone, have no effect on OC symptom intensity.
5HT1A receptor Neg (no) Regulation (effect) of OC associated with agonist
1) Confidence 0.03 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2416754 Disease Relevance 0.23 Pain Relevance 0.51

General Comments

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