INT235498

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.17
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (IL15) aging (IL15) Golgi apparatus (IL15)
cell-cell signaling (IL15) cytoplasm (IL15) extracellular space (IL15)
Anatomy Link Frequency
T lymphocytes 2
monocytes 1
skeletal muscles 1
IL15 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 72 100.00 Very High Very High Very High
chemokine 10 67.12 Quite High
cOX1 3 65.40 Quite High
ketamine 2 60.28 Quite High
anesthesia 2 58.80 Quite High
Inflammation 11 21.56 Low Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
sodium channel 5 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 12 98.40 Very High Very High Very High
Cancer 69 94.48 High High
Infection 167 93.40 High High
Malaria 163 90.80 High High
Non-small-cell Lung Cancer 18 90.16 High High
Adenocarcinoma 53 73.08 Quite High
Communicable Diseases 2 71.40 Quite High
Severe Combined Immunodeficiency 6 50.84 Quite High
Disease Progression 14 50.00 Quite Low
Immunodeficiency 4 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, IL-15 which is highly expressed in neural tissues and skeletal muscles [27] is released in large quantities following physical stress [28,29].
Localization (released) of IL-15 in skeletal muscles associated with stress
1) Confidence 0.21 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0.16 Pain Relevance 0.05
Such improved interaction has been shown to be mediated by another cytokine, interleukin 15 (IL-15) resulting in increased IL-2 production by T lymphocytes, such as observed in our study.
Localization (resulting) of IL-15 in T lymphocytes associated with cytokine
2) Confidence 0.20 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0.08 Pain Relevance 0.05
Such improved interaction has been shown to be mediated by another cytokine, interleukin 15 (IL-15) resulting in increased IL-2 production by T lymphocytes, such as observed in our study.
Localization (resulting) of interleukin 15 in T lymphocytes associated with cytokine
3) Confidence 0.20 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0.08 Pain Relevance 0.05
When DCs or monocytes-macrophages encounter a pathogen and release cytokines such as IL-12, IL-15, IL-18, TNF-?
Localization (release) of IL-15 in monocytes associated with cytokine
4) Confidence 0.13 Published 2009 Journal Parasite Immunology Section Body Doc Link PMC2759986 Disease Relevance 0.67 Pain Relevance 0.05
1, and increasing release of TNF, IL-15 and IL-18.
Localization (release) of IL-15
5) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2702099 Disease Relevance 0.89 Pain Relevance 0.10
Priming injections of separate Ad5-based vectors expressing codon-optimized SIVmac239 gag, env and nef with and without rhesus IL-15.FLAG or empty Ad-?
Localization (optimized) of IL-15
6) Confidence 0.05 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC3009592 Disease Relevance 0.29 Pain Relevance 0.09

General Comments

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