INT2355

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Context Info
Confidence 0.26
First Reported 1975
Last Reported 2009
Negated 2
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 2.50
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Klkb1) extracellular space (Klkb1) extracellular region (Klkb1)
molecular_function (Klkb1) cellular_component (Klkb1) biological_process (Klkb1)
Anatomy Link Frequency
plasma 6
Klkb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 3 98.92 Very High Very High Very High
Intracerebroventricular 1 98.46 Very High Very High Very High
agonist 4 95.56 Very High Very High Very High
antagonist 7 95.04 Very High Very High Very High
anesthesia 1 85.52 High High
narcan 2 81.20 Quite High
Enkephalin 3 80.28 Quite High
local anesthetic 1 76.72 Quite High
opioid receptor 1 75.00 Quite High
Kappa opioid receptor 2 74.68 Quite High
Disease Link Frequency Relevance Heat
Obstructive Jaundice 48 97.28 Very High Very High Very High
Pancreatitis 52 97.14 Very High Very High Very High
Phobia 4 95.64 Very High Very High Very High
Anxiety Disorder 4 95.36 Very High Very High Very High
Injury 8 95.28 Very High Very High Very High
Panic Disorder 1 85.76 High High
Syndrome 1 74.24 Quite High
INFLAMMATION 6 70.48 Quite High
Convulsion 1 69.00 Quite High
Akathisia 1 66.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Diminished suppression of plasma MHPG concentrations in two subjects was associated with the continued emergence of panic symptoms in response to phobic stimuli.
Negative_regulation (suppression) of plasma MHPG in plasma associated with phobia
1) Confidence 0.26 Published 1983 Journal Arch. Gen. Psychiatry Section Abstract Doc Link 6838322 Disease Relevance 0.75 Pain Relevance 0.25
T3 also antagonized the pentobarbital-induced release of GH; however, plasma B levels were not modified, and the effect on plasma GH levels was not suppressed by propranolol.
Neg (not) Negative_regulation (suppressed) of plasma B in plasma
2) Confidence 0.07 Published 1975 Journal Endocr Res Commun Section Abstract Doc Link 806447 Disease Relevance 0 Pain Relevance 0.09
In contrast, the administration of ethanol alone or ethanol with 4-methylpyrazole resulted in a decrease in plasma MLI concentrations.
Negative_regulation (decrease) of plasma MLI in plasma
3) Confidence 0.02 Published 1989 Journal J. Endocrinol. Section Abstract Doc Link 2926314 Disease Relevance 0 Pain Relevance 0.14
The plasma procainesterase activity of patients who had experienced systemic toxic reactions was significantly decreased as compared to that of controls, an observation not previously reported.
Negative_regulation (decreased) of plasma procainesterase in plasma
4) Confidence 0.02 Published 1978 Journal Sex Transm Dis Section Abstract Doc Link 417409 Disease Relevance 0.45 Pain Relevance 0.08
After treatment with Salvia miltiorrhizae, the contents of plasma endotoxin in SAP and OJ rats in treated group were significantly lower than those in model control group, indicating that Salvia miltiorrhizae can effectively decrease the levels of plasma endotoxin.
Negative_regulation (decrease) of plasma endotoxin in plasma associated with pancreatitis and obstructive jaundice
5) Confidence 0.02 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2790077 Disease Relevance 1.29 Pain Relevance 0.04
Intracerebroventricular (i.c.v.) administration of DALDA (0.5 and 5 micrograms/kg) but not U-69,593 suppressed both plasma hormone levels 30 min after injection.
Neg (not) Negative_regulation (suppressed) of plasma hormone in plasma associated with intracerebroventricular
6) Confidence 0.02 Published 1991 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1665795 Disease Relevance 0 Pain Relevance 0.71

General Comments

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