INT235561

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GRIA1) endoplasmic reticulum (GRIA1) plasma membrane (GRIA1)
GRIA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate receptor 10 99.76 Very High Very High Very High
nMDA receptor 15 87.52 High High
Pain 5 84.72 Quite High
Kinase C 13 80.32 Quite High
GABAergic 16 72.48 Quite High
substance P 2 65.04 Quite High
Glutamate 4 64.40 Quite High
Neurotransmitter 10 63.60 Quite High
Sciatic nerve 7 61.48 Quite High
c fibre 26 59.40 Quite High
Disease Link Frequency Relevance Heat
Nociception 5 90.40 High High
Pain 5 84.72 Quite High
Li-fraumeni Syndrome 24 60.64 Quite High
Disease 6 50.00 Quite Low
Adhesions 3 32.68 Quite Low
Hyperalgesia 15 15.56 Low Low
Depression 8 5.00 Very Low Very Low Very Low
Neurological Disease 7 5.00 Very Low Very Low Very Low
Epilepsy 7 5.00 Very Low Very Low Very Low
Intellectual Impairment 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, targeting of guanylate kinase domain-associated protein (GKAP) and AMPA-type glutamate receptors are dependent on the availability of PSD-95 (El-Husseini et al., 2000; Gerrow et al., 2006).
Localization (targeting) of AMPA associated with glutamate receptor
1) Confidence 0.06 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2526001 Disease Relevance 0 Pain Relevance 0.23
Its activity is also necessary for translocation of AMPA receptors to the subsynaptic membrane [48].
Localization (translocation) of AMPA
2) Confidence 0.01 Published 2008 Journal Mol Pain Section Body Doc Link PMC2424039 Disease Relevance 0.37 Pain Relevance 0.45

General Comments

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