INT235604

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1a, Htr3a) cytoplasm (Htr3a) signal transducer activity (Htr1a)
Anatomy Link Frequency
brain 1
Htr1a (Rattus norvegicus)
Htr3a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 4 100.00 Very High Very High Very High
antidepressant 36 97.40 Very High Very High Very High
sSRI 22 94.80 High High
fluoxetine 11 91.40 High High
Serotonin 8 90.28 High High
Onset of action 3 78.44 Quite High
midbrain 1 59.84 Quite High
Raphe 1 49.16 Quite Low
depression 33 44.92 Quite Low
agonist 5 39.12 Quite Low
Disease Link Frequency Relevance Heat
Depression 35 44.92 Quite Low
Urological Neuroanatomy 2 31.04 Quite Low
Anxiety Disorder 1 27.92 Quite Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 4 5.00 Very Low Very Low Very Low
Recurrence 3 5.00 Very Low Very Low Very Low
Depressive Disorder 2 5.00 Very Low Very Low Very Low
Mental Disorders 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-adrenergic/5-HT1A receptor antagonist, pindolol, which binds to the 5-HT1A receptors in the human brain (Martinez et al 2001; Rabiner et al 2001), accelerates and may enhance the antidepressant effect of SSRIs (meta-analysis of Ballesteros and Callado 2004; review of Isaac 2004), such as fluoxetine (see review of Artigas et al 2001; controlled trial, PĂ©rez et al 2001), or in paroxetine-refractory patients (placebo-controlled study, Sokolski et al 2004).
5-HT1A Binding (binds) of 5-HT1A receptor in brain associated with antidepressant, antagonist, ssri and fluoxetine
1) Confidence 0.01 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2424118 Disease Relevance 0 Pain Relevance 0.74

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox