INT235743

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.14
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Tradd) cytoplasm (Tradd)
Tradd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 4 59.32 Quite High
Inflammatory response 8 54.96 Quite High
Inflammation 6 8.12 Low Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 102 100.00 Very High Very High Very High
Necrosis 10 100.00 Very High Very High Very High
Cancer 10 100.00 Very High Very High Very High
Apoptosis 62 97.84 Very High Very High Very High
Injury 64 74.80 Quite High
Optic Nerve Injuries 68 73.60 Quite High
Glaucoma 2 60.96 Quite High
Cv Unclassified Under Development 4 59.32 Quite High
INFLAMMATION 14 54.56 Quite High
Ocular Hypertension 2 46.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, the expression pattern and regulation of TNFR1a, TRADD, and the executioner protease, Caspase 3, indicate that the extrinsic pathway to apoptosis [43] is active in RGCs undergoing IONT or IONC.
Regulation (regulation) of TRADD associated with apoptosis
1) Confidence 0.49 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 0.97 Pain Relevance 0.06
For this reason, we also measured the regulation of tumor necrosis factor associated death domain (TRADD), which links TNFR1a and TNFR12A (Fn14) signaling to apoptosis [29,30].
Regulation (regulation) of TRADD associated with necrosis, cancer, apoptosis and death
2) Confidence 0.49 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 1.17 Pain Relevance 0

General Comments

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