INT235755

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Ppm1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 4 73.28 Quite High
cva 54 64.00 Quite High
Spinal cord 1 53.28 Quite High
Central nervous system 1 50.32 Quite High
Inflammatory response 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 31 99.72 Very High Very High Very High
Necrosis 5 88.20 High High
Cancer 5 87.84 High High
Death 52 79.76 Quite High
INFLAMMATION 8 73.28 Quite High
Injury 39 73.20 Quite High
Stress 4 64.80 Quite High
Optic Nerve Injuries 34 64.48 Quite High
Cv General 4 Under Development 54 64.00 Quite High
Retina Disease 4 56.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pro-apoptotic genes, associated to the intrinsic apoptotic pathway, are regulated after IONT and IONC (14–3–3, RAD9, RASSF4, Rb protein, Smad4, PPM1B), although IONT (BMF, Bcl.10, Bax, Bcl-B, DLC1, MCL1) seems to trigger a higher response than IONC does.
Spec (seems) Regulation (regulated) of PPM1B associated with apoptosis
1) Confidence 0.20 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2426719 Disease Relevance 1.29 Pain Relevance 0.09
Accordingly, the values for B2MG, GUSB and POL2R were removed from the geNorm input file and the stability of GAPDH, HPRT, SDHA and TBP were re-assessed.
Regulation (values) of B2MG
2) Confidence 0.01 Published 2010 Journal BMC Mol Biol Section Body Doc Link PMC2823748 Disease Relevance 0.12 Pain Relevance 0.06

General Comments

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