INT23576

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Context Info
Confidence 0.18
First Reported 1986
Last Reported 1986
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Crh) extracellular space (Crh) response to stress (Crh)
cytoplasm (Crh)
Anatomy Link Frequency
median eminence 2
nucleus 1
Penk (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 3 100.00 Very High Very High Very High
5HT 3 100.00 Very High Very High Very High
Cholecystokinin 5 91.40 High High
Neurotransmitter 2 75.00 Quite High
Somatostatin 4 68.16 Quite High
substance P 4 66.08 Quite High
Calcitonin gene-related peptide 3 61.32 Quite High
Neuropeptide 1 30.80 Quite Low
Dopamine 1 28.24 Quite Low
Serotonin 1 27.60 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ultrastructural localizations of rat corticoliberin (rCRF) and methionine-enkephalin octapeptide (Met-Enk-8) in the external layer of the rat median eminence were examined by double-immunogold labeling with anti-rCRF and anti-Met-Enk-8 sera labeled with small-sized (Gs) and medium-sized (Gm) gold particles, respectively.
anti-Met-Enk-8 Binding (labeling) of rCRF in median eminence associated with enkephalin
1) Confidence 0.18 Published 1986 Journal Brain Res. Section Abstract Doc Link 2423180 Disease Relevance 0 Pain Relevance 0.10
The ultrastructural localizations of rat corticoliberin (rCRF) and methionine-enkephalin octapeptide (Met-Enk-8) in the external layer of the rat median eminence were examined by double-immunogold labeling with anti-rCRF and anti-Met-Enk-8 sera labeled with small-sized (Gs) and medium-sized (Gm) gold particles, respectively.
Met-Enk-8 Spec (examined) Binding (labeling) of rCRF in median eminence associated with enkephalin
2) Confidence 0.18 Published 1986 Journal Brain Res. Section Abstract Doc Link 2423180 Disease Relevance 0 Pain Relevance 0.10
The major inputs to the MPNl studied here appear to be stained with antisera to 5HT and L-ENK, although moderate numbers of NT- and CRF- immunoreactive fibers were also found in this part of the nucleus.
L-ENK Binding (antisera) of CRF in nucleus associated with 5ht
3) Confidence 0.16 Published 1986 Journal J. Comp. Neurol. Section Abstract Doc Link 2422228 Disease Relevance 0 Pain Relevance 0.42

General Comments

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