INT235869

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc6a4, Ppp2ca) plasma membrane (Slc6a4, Ppp2ca) endosome (Slc6a4)
transport (Slc6a4) cytoplasm (Ppp2ca) chromosome (Ppp2ca)
Anatomy Link Frequency
PP2A 1
Slc6a4 (Mus musculus)
Ppp2ca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 15 96.20 Very High Very High Very High
depression 34 90.16 High High
monoamine 5 86.68 High High
sSRI 91 69.72 Quite High
Serotonin 8 55.04 Quite High
antidepressant 39 50.00 Quite Low
Neurotransmitter 10 5.00 Very Low Very Low Very Low
Calcium channel 6 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 40 90.16 High High
Suicidal Behaviour 5 65.08 Quite High
Disease 2 52.44 Quite High
Affective Disorder 12 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, SERT co-exists in a complex with protein phosphatase 2A (PP2A), and dephosphorylation by PP2A can increase transporter activity at the cell surface (Bauman et al 2000).
SERT Binding (complex) of PP2A in PP2A
1) Confidence 0.04 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2426818 Disease Relevance 0.21 Pain Relevance 0.31

General Comments

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