INT235874

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Camk2a, Slc6a4) cytosol (Slc6a4) endosome (Slc6a4)
transport (Slc6a4) kinase activity (Camk2a) cytoplasm (Camk2a)
Camk2a (Mus musculus)
Slc6a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 15 87.84 High High
depression 34 80.72 Quite High
monoamine 5 77.24 Quite High
Serotonin 8 71.36 Quite High
sSRI 91 60.28 Quite High
antidepressant 39 50.00 Quite Low
antagonist 5 6.56 Low Low
Neurotransmitter 10 5.00 Very Low Very Low Very Low
Calcium channel 6 5.00 Very Low Very Low Very Low
potassium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 40 80.72 Quite High
Suicidal Behaviour 5 55.64 Quite High
Disease 2 43.00 Quite Low
Affective Disorder 12 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylation by calcium/calmodulin-dependent protein kinase II (CAMKII) may also enhance SERT activity (Yura et al 1996), as can various tyrosine kinases (Helmeste and Tang 1995).
CAMKII Spec (may) Positive_regulation (enhance) of SERT
1) Confidence 0.11 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2426818 Disease Relevance 0.14 Pain Relevance 0.28

General Comments

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