INT235876

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkca) endoplasmic reticulum (Prkca) enzyme binding (Prkca)
extracellular matrix organization (Hspg2) protein complex (Prkca) cytoplasm (Prkca)
Hspg2 (Mus musculus)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 15 100.00 Very High Very High Very High
depression 34 96.40 Very High Very High Very High
sSRI 91 91.40 High High
fluoxetine 2 86.08 High High
Dopamine 3 78.00 Quite High
antidepressant 39 70.72 Quite High
Nucleus accumbens 1 53.12 Quite High
Central nervous system 1 19.84 Low Low
Neurotransmitter 10 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 40 96.40 Very High Very High Very High
Manic Depressive Disorder 3 79.20 Quite High
Leukemia 1 58.08 Quite High
Affective Disorder 12 38.16 Quite Low
Stress 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Suicidal Behaviour 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PLC, via creation of diacylglyceral, then activates PKC.
PLC Positive_regulation (activates) of PKC associated with kinase c
1) Confidence 0.03 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2426818 Disease Relevance 0.23 Pain Relevance 0.53

General Comments

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