INT23589

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Context Info
Confidence 0.67
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 11
Disease Relevance 6.73
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (CALCR) plasma membrane (CALCR) signal transducer activity (CALCR)
Anatomy Link Frequency
plasma 1
Liver 1
CALCR (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 96.76 Very High Very High Very High
imagery 11 95.48 Very High Very High Very High
carpal tunnel syndrome 51 95.12 Very High Very High Very High
Neurolysis 3 70.64 Quite High
Regional anesthesia 3 50.24 Quite High
anesthesia 4 49.32 Quite Low
positron emission tomography 1 42.28 Quite Low
cytokine 12 26.16 Quite Low
Pain 39 10.32 Low Low
Inflammation 15 8.48 Low Low
Disease Link Frequency Relevance Heat
Carpal Tunnel Syndrome 102 100.00 Very High Very High Very High
Lymphatic Filariasis 4 100.00 Very High Very High Very High
Esophageal Cancer 34 99.72 Very High Very High Very High
Cicatrix 24 98.00 Very High Very High Very High
Hepatotoxicity 2 97.86 Very High Very High Very High
Keloid Scars 15 97.84 Very High Very High Very High
Pancreatic Cancer 4 97.64 Very High Very High Very High
Injury 30 97.24 Very High Very High Very High
Pancreatitis 6 96.76 Very High Very High Very High
Sprains And Strains 165 96.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Liver damage seems to play a role in increasing serum IRT levels of patients without pancreatic involvement, while the increased Ctr/Ccr seems to depend on other factors, for instance renal tubular dysfunction.
Positive_regulation (increased) of Ctr in Liver associated with hepatotoxicity
1) Confidence 0.67 Published 1985 Journal Ric Clin Lab Section Abstract Doc Link 2422720 Disease Relevance 0.87 Pain Relevance 0.16
Elevated Ctr/Ccr and IRT values were observed in several patients with pancreatic cancer and chronic pancreatitis.
Positive_regulation (Elevated) of Ctr associated with pancreatic cancer and chronic pancreatitis
2) Confidence 0.49 Published 1985 Journal Ric Clin Lab Section Abstract Doc Link 2422720 Disease Relevance 0.96 Pain Relevance 0.19
Open CTR
Positive_regulation (Open) of CTR
3) Confidence 0.29 Published 2007 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC2981897 Disease Relevance 0.27 Pain Relevance 0.12
Local wound problems in terms of scarring or scar tenderness were significantly more pronounced in patients undergoing open CTR compared to patients undergoing endoscopic CTR.
Positive_regulation (undergoing) of CTR associated with cicatrix, injury and keloid scars
4) Confidence 0.27 Published 2007 Journal Indian Journal of Orthopaedics Section Abstract Doc Link PMC2981897 Disease Relevance 0.76 Pain Relevance 0.33
Average delay to return to normal activity was appreciably less in group undergoing endoscopic CTR.
Positive_regulation (undergoing) of CTR
5) Confidence 0.27 Published 2007 Journal Indian Journal of Orthopaedics Section Abstract Doc Link PMC2981897 Disease Relevance 0.71 Pain Relevance 0.31
Levine et al., performed an FDG-PET at diagnosis and following CRT in 31 oesophageal cancer patients [81].
Positive_regulation (following) of CRT associated with esophageal cancer
6) Confidence 0.24 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1999497 Disease Relevance 1.06 Pain Relevance 0.05
OBJECTIVE: To describe how clinical practice in those who underwent carpal tunnel release (CTR) matched the American Association of Electrodiagnostic Medicine (AAEM) 1993 practice parameters for electrodiagnostic evaluation of carpal tunnel syndrome (CTS).
Positive_regulation (underwent) of CTR associated with carpal tunnel syndrome
7) Confidence 0.09 Published 2005 Journal Arch Phys Med Rehabil Section Abstract Doc Link 15640981 Disease Relevance 0.27 Pain Relevance 0.10
PARTICIPANTS: State Medicare beneficiaries who underwent CTR in 1999 (N=1567) Interventions Not applicable.
Positive_regulation (underwent) of CTR
8) Confidence 0.06 Published 2005 Journal Arch Phys Med Rehabil Section Body Doc Link 15640981 Disease Relevance 0.09 Pain Relevance 0
CONCLUSIONS: Over one third of Medicare patients undergoing CTR in Washington State in 1999 may have had an inappropriate electrodiagnostic workup before the surgery.
Positive_regulation (undergoing) of CTR
9) Confidence 0.06 Published 2005 Journal Arch Phys Med Rehabil Section Body Doc Link 15640981 Disease Relevance 0.05 Pain Relevance 0
In contrast, HWI in 8-wk old C57BL/6J males infused with 40 mg/kg iso for seven days increased from 5.0 in ctr to 6.0 mg/g (i.e. a relative increase of 22%) in treated animals [23].
Positive_regulation (increased) of ctr
10) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722085 Disease Relevance 0.53 Pain Relevance 0
Consistent with this finding, bacterial instillation led to a significant increase in total plasma equivalents (TPE) compared to the CTR group (0.22 ± 0.03 vs. 0.07 ± 0.03, p < 0.05). rhAPC administration increased TPE in the A-PNP group compared to the PNP group, but this increase remained below a statistical significance (0.37 ± 0.15 vs. 0.22 ± 0.03, p = 0.33) (Figure 2).


Positive_regulation (increase) of CTR in plasma associated with lymphatic filariasis and pneumonia
11) Confidence 0.02 Published 2006 Journal Respir Res Section Body Doc Link PMC1435891 Disease Relevance 1.15 Pain Relevance 0

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