INT23590

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Context Info
Confidence 0.26
First Reported 1985
Last Reported 2007
Negated 1
Speculated 1
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 1.05
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (CALCR) plasma membrane (CALCR) signal transducer activity (CALCR)
Anatomy Link Frequency
osteoclast 2
CALCR (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 5 99.56 Very High Very High Very High
Chronic pancreatitis 2 97.52 Very High Very High Very High
depression 1 84.24 Quite High
noradrenaline 1 75.00 Quite High
Analgesic 2 25.00 Low Low
alcohol 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Mechanotransduction 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 2 98.40 Very High Very High Very High
Pancreatitis 3 97.52 Very High Very High Very High
Disorders Of Creatine Metabolism 3 94.00 High High
Disease 2 92.80 High High
Depression 1 84.24 Quite High
Hepatotoxicity 1 74.40 Quite High
Osteoporosis 3 50.00 Quite Low
Sprains And Strains 19 43.60 Quite Low
Hypercalcemia 4 5.00 Very Low Very Low Very Low
Depressive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevated Ctr/Ccr and IRT values were observed in several patients with pancreatic cancer and chronic pancreatitis.
Regulation (values) of Ctr associated with pancreatic cancer and chronic pancreatitis
1) Confidence 0.26 Published 1985 Journal Ric Clin Lab Section Abstract Doc Link 2422720 Disease Relevance 0.96 Pain Relevance 0.19
However, clonidine was unable to induce changes in CRT, GH, and PRL mean levels in any depressed group.
Neg (unable) Regulation (changes) of CRT associated with clonidine
2) Confidence 0.26 Published 1985 Journal Neuroendocrinology Section Abstract Doc Link 4047333 Disease Relevance 0.08 Pain Relevance 0.52
The prolonged decrease in CTR mRNA levels suggests that recovery may require new osteoclast formation, and indicates that regulation of the CTR in cells of the osteoclast lineage is different from that in nonosteoclastic cells and tissues.
Regulation (regulation) of CTR in osteoclast
3) Confidence 0.11 Published 1995 Journal Bone Section Abstract Doc Link 8579955 Disease Relevance 0 Pain Relevance 0
The aim of this study was to investigate homologous regulation of the CTR, and regulation of TRAP expression in osteoclast-like cells after brief treatment with salmon CT (sCT).
Spec (investigate) Regulation (regulation) of CTR in osteoclast
4) Confidence 0.11 Published 1995 Journal Bone Section Abstract Doc Link 8579955 Disease Relevance 0 Pain Relevance 0
Both groups, however, were significantly different from AGE-CTR which gained 2% (p?
Regulation (different) of CTR
5) Confidence 0.03 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1919432 Disease Relevance 0 Pain Relevance 0

General Comments

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