INT235949

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Aqp4) protein complex (Aqp4) transmembrane transport (Aqp4)
cytoplasm (Aqp4)
Anatomy Link Frequency
extracellular matrix 2
Aqp4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 61 68.48 Quite High
Spinal cord 28 5.00 Very Low Very Low Very Low
Neuritis 25 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
Multiple sclerosis 16 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 215 50.00 Quite Low
Disease 52 43.36 Quite Low
Multiple Sclerosis 31 5.00 Very Low Very Low Very Low
Optic Neuritis 24 5.00 Very Low Very Low Very Low
Autoimmune Disease 22 5.00 Very Low Very Low Very Low
Infection 19 5.00 Very Low Very Low Very Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Transverse Myelitis 14 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Complex transmembrane, cytoskeletal and extracellular matrix components (agrin, heparan sulfate proteoglycan; laminin, extracellular matrix protein) regulate access of AQP4 to the apical domain of astrocytes where different lipid species and additional membrane proteins (e.g., K+ leak channels) share the "domain space" with complex arrays of AQP4.
Regulation (regulate) of Positive_regulation (access) of AQP4 in extracellular matrix
1) Confidence 0.37 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2427020 Disease Relevance 0 Pain Relevance 0.03

General Comments

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