INT235960

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Aqp4, H47) endoplasmic reticulum (H47) plasma membrane (Aqp4)
enzyme binding (H47) protein complex (Aqp4) transmembrane transport (Aqp4)
Aqp4 (Rattus norvegicus)
H47 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 61 29.80 Quite Low
Multiple sclerosis 16 10.32 Low Low
Spinal cord 28 6.56 Low Low
Neuritis 25 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 215 73.44 Quite High
Disease 52 42.52 Quite Low
Multiple Sclerosis 31 10.32 Low Low
Optic Neuritis 24 5.00 Very Low Very Low Very Low
Autoimmune Disease 22 5.00 Very Low Very Low Very Low
Infection 19 5.00 Very Low Very Low Very Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Transverse Myelitis 14 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the tetramer model, individual AQP4 subunits are proposed to interact with each other via residues (R108, G157, W231 I239, Y250) in the H4 and H6 helices [25].
AQP4 Binding (interact) of H4
1) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2427020 Disease Relevance 0.13 Pain Relevance 0

General Comments

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