INT235963

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Snta1, Aqp4) cytoplasm (Snta1, Aqp4) cytoskeleton (Snta1)
intracellular (Snta1) protein complex (Aqp4) transmembrane transport (Aqp4)
Snta1 (Mus musculus)
Aqp4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 61 99.68 Very High Very High Very High
Spinal cord 28 5.00 Very Low Very Low Very Low
Neuritis 25 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
Multiple sclerosis 16 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 215 80.64 Quite High
Disease 52 74.24 Quite High
Multiple Sclerosis 31 5.00 Very Low Very Low Very Low
Optic Neuritis 24 5.00 Very Low Very Low Very Low
Autoimmune Disease 22 5.00 Very Low Very Low Very Low
Infection 19 5.00 Very Low Very Low Very Low
INFLAMMATION 18 5.00 Very Low Very Low Very Low
Targeted Disruption 18 5.00 Very Low Very Low Very Low
Transverse Myelitis 14 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-syntrophin is not fatal to mice but the loss of expression does influence AQP4 expression in the CNS.
syntrophin Regulation (influence) of Gene_expression (expression) of AQP4 associated with central nervous system
1) Confidence 0.41 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2427020 Disease Relevance 0.23 Pain Relevance 0.05

General Comments

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