INT235976

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.62
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APC) chromosome organization (APC) cell adhesion (APC)
plasma membrane (APC) cytoskeleton (APC) nucleus (APC)
Anatomy Link Frequency
T-cell 2
APC 1
APC (Homo sapiens)
Trav6-3 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 25 72.24 Quite High
Inflammation 19 67.76 Quite High
Multiple sclerosis 16 45.88 Quite Low
Central nervous system 61 45.04 Quite Low
cytokine 45 15.08 Low Low
Spinal cord 28 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
intrathecal 2 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 359 91.40 High High
Infection 23 83.84 Quite High
Death 8 81.60 Quite High
Apoptosis 3 81.04 Quite High
Necrosis 4 80.00 Quite High
Neuromyelitis Optica 215 77.96 Quite High
Transverse Myelitis 14 72.60 Quite High
Optic Neuritis 24 72.24 Quite High
INFLAMMATION 20 67.76 Quite High
Targeted Disruption 28 61.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first signal is mediated by the interaction between the peptide/MHC complex on the surface of antigen presenting cells (APC) and the T-cell receptor (TCR) on the surface of T-cells.
APC Binding (complex) of TCR in T-cell
1) Confidence 0.01 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2840411 Disease Relevance 0.74 Pain Relevance 0
The first signal is mediated by the interaction between the peptide/MHC complex on the surface of antigen presenting cells (APC) and the T-cell receptor (TCR) on the surface of T-cells.
APC Binding (complex) of TCR in T-cell
2) Confidence 0.01 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2840411 Disease Relevance 0.74 Pain Relevance 0
Immune responses are dependent on lymphocytes that express antigen-specific or antigen-crossreactive TCR and BCR interacting with the APC they encounter while trafficking in the secondary lymphoid tissue.
APC Binding (interacting) of TCR in APC
3) Confidence 0.00 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2427020 Disease Relevance 1.14 Pain Relevance 0.24

General Comments

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