INT236003

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR1A, Grin1) enzyme binding (Grin1) cytoplasm (Grin1)
signal transducer activity (HTR1A)
HTR1A (Homo sapiens)
Grin1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pyramidal cell 40 96.68 Very High Very High Very High
antidepressant 6 89.56 High High
antagonist 22 80.16 Quite High
Serotonin 60 79.28 Quite High
Glutamate receptor 2 72.48 Quite High
Glutamate 14 57.56 Quite High
tetrodotoxin 2 30.96 Quite Low
Central nervous system 2 21.08 Low Low
5HT 90 5.00 Very Low Very Low Very Low
fluoxetine 48 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 6 82.40 Quite High
Mental Disorders 4 76.32 Quite High
Cognitive Disorder 10 70.16 Quite High
Aggression 2 31.00 Quite Low
Anxiety Disorder 2 29.88 Quite Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Rupture 2 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It remains unknown whether 5-HT2A receptor activation has any impact on the 5-HT1A-NMDAR interaction.
5-HT1A Binding (interaction) of NMDAR
1) Confidence 0.01 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427346 Disease Relevance 0.35 Pain Relevance 0.32
It remains unknown whether 5-HT2A receptor activation has any impact on the 5-HT1A-NMDAR interaction.
5-HT1A Binding (interaction) of NMDAR
2) Confidence 0.01 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427346 Disease Relevance 0.35 Pain Relevance 0.32

General Comments

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