INT236004

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (MAPK1, Map2) cytoplasm (MAPK1, Map2) cytoskeleton (MAPK1, Map2)
nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)
MAPK1 (Homo sapiens)
Map2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 15 90.80 High High
5HT 45 75.40 Quite High
Glutamate 7 74.24 Quite High
nMDA receptor 8 26.12 Quite Low
Pyramidal cell 20 6.64 Low Low
Serotonin 30 5.00 Very Low Very Low Very Low
fluoxetine 24 5.00 Very Low Very Low Very Low
antagonist 11 5.00 Very Low Very Low Very Low
antidepressant 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 5 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Mental Disorders 2 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Rupture 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we speculate that 5-HT2 receptors might activate ERK, leading to increased phosphorylation of MAP2 and its association with microtubules.
Spec (27928) Positive_regulation (activate) of ERK Positive_regulation (leading) of Phosphorylation (phosphorylation) of MAP2
1) Confidence 0.04 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427346 Disease Relevance 0 Pain Relevance 0.24

General Comments

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