INT236016

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.81
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK8) cell differentiation (ROS1) mitochondrion (MAPK8)
response to stress (MAPK8) cytoplasm (MAPK8) cell proliferation (ROS1)
Anatomy Link Frequency
plaques 1
ROS1 (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 49 46.72 Quite Low
cytokine 22 5.00 Very Low Very Low Very Low
fibrosis 19 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Amyloid Plaque 35 97.96 Very High Very High Very High
Alzheimer's Dementia 36 95.12 Very High Very High Very High
Death 60 92.96 High High
Targeted Disruption 5 91.08 High High
Apoptosis 55 89.48 High High
Stress 124 85.24 High High
Wound Healing 12 50.00 Quite Low
INFLAMMATION 58 46.72 Quite Low
Liver Disease 43 44.68 Quite Low
Injury 46 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Excessive ROS stimulate JNK activity in susceptible neurons that surround the amyloid plaques.
ROS Positive_regulation (stimulate) of JNK in plaques associated with amyloid plaque
1) Confidence 0.18 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2427353 Disease Relevance 1.08 Pain Relevance 0
Several mechanisms have been described to explain ROS-mediated activation of JNK but three should be considered.
ROS-mediated Positive_regulation (activation) of JNK
2) Confidence 0.05 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.73 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox