INT236074

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Context Info
Confidence 0.28
First Reported 2008
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 9
Total Number 11
Disease Relevance 11.40
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DARC) signal transducer activity (DARC)
Anatomy Link Frequency
erythrocytes 1
DARC (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 15 25.00 Low Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malaria 1545 100.00 Very High Very High Very High
Infection 325 100.00 Very High Very High Very High
Recurrence 51 99.92 Very High Very High Very High
Coma 21 95.04 Very High Very High Very High
Disease 94 94.48 High High
Neurologic Manifestations 2 89.88 High High
Anaemia 44 84.32 Quite High
Convulsion 6 76.80 Quite High
Respiratory Distress 28 76.00 Quite High
Parasitic Infection 11 43.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparing the rate of each neurological sign between P. vivax and P. falciparum SM, fits were as frequent in both species (22% for both, ?
Gene_expression (frequent) of vivax associated with malaria
1) Confidence 0.28 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2429951 Disease Relevance 1.75 Pain Relevance 0
As shown in Figure 5 (restricted to children < 5 y), total parasite densities were indeed significantly higher in children with mixed infections than in those with P. falciparum or P. vivax monoinfections, whether all cases (t = ?
Spec (whether) Gene_expression (monoinfections) of vivax associated with infection
2) Confidence 0.28 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2429951 Disease Relevance 1.16 Pain Relevance 0
Another element that indicate that most multiple vivax clinical episodes in the same patient area dependent of relapses and not of re infections is that multiple vivax episodes registered in Candelária, in 2005 and 2006 occurred in the same house and frequently in the same person (data not shown).


Gene_expression (episodes) of vivax associated with infection and recurrence
3) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 1.20 Pain Relevance 0
Figure 4 summarizes the seasonal incidence of P. vivax and P. falciparum malaria in Candelária (Figure 4A) and Teotônio (Figure 4B), as well as the density of Anophelines, expresses in hourly biting rate (HBR).
Gene_expression (expresses) of vivax associated with malaria
4) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 1.27 Pain Relevance 0
In the one year period of observation falciparum clinical attacks were usually unique (just one exception) while in 2005, for instance, 17 residents presented 2 clinical episodes and 6 residents presented 3 vivax clinical episodes
Gene_expression (episodes) of vivax
5) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 1.17 Pain Relevance 0
If this is suggestive of indoors transmission (since no special protective physical structures were found associated with “negative houses”), the concentration may be dependent on other factors, including some registered in other items of the manuscript such as: (i) the number of inhabitants per house in the positive dwellings; (ii) the relapses of vivax malaria in the “positive houses” considering, for instance, that 97 vivax malaria cases occurred in Vila Candelaria in 2005 in only 67 patients and 79 vivax malaria cases occurred in only 64 patients in 2006 (Tables 4 and 5).
Gene_expression (malaria) of vivax associated with malaria and recurrence
6) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 0.81 Pain Relevance 0
Another element that indicate that most multiple vivax clinical episodes in the same patient area dependent of relapses and not of re infections is that multiple vivax episodes registered in Candelária, in 2005 and 2006 occurred in the same house and frequently in the same person (data not shown).


Gene_expression (episodes) of vivax associated with infection and recurrence
7) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 1.21 Pain Relevance 0
If all the multiple vivax clinical attacks in the same patients were considered relapses, it would reduce the 97 vivax episodes in Candelária of 2005 to 67 vivax episodes produced by original infections (97?
Gene_expression (produced) of vivax associated with infection and recurrence
8) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821918 Disease Relevance 1.19 Pain Relevance 0
The parasite structure found inside the erythrocytes was compatible with Plasmodium which suggested a possible infection by Plasmodium, in agreement with multiplex Real time quantitative PCR results (Figure 2).
Spec (possible) Gene_expression (infection) of Plasmodium in erythrocytes associated with infection
9) Confidence 0.04 Published 2010 Journal Malar J Section Body Doc Link PMC2921078 Disease Relevance 0.45 Pain Relevance 0
In a rapid diagnostic test for malaria (Binax Now Malaria Test; Binax, Inc., USA), the sample was both negative for P. falciparum histidine-rich protein 2 and for pan-malarial aldolase antigen, suggesting a non-Plasmodium infection.
Gene_expression (infection) of Plasmodium associated with malaria
10) Confidence 0.04 Published 2010 Journal Malar J Section Body Doc Link PMC2921078 Disease Relevance 0.44 Pain Relevance 0
Multidrug-resistant Plasmodium vivax (Pv) is widespread in eastern Indonesia, and emerging elsewhere in Asia-Pacific and South America, but is generally regarded as a benign disease.
Gene_expression (resistant) of vivax associated with malaria and disease
11) Confidence 0.03 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2429950 Disease Relevance 0.74 Pain Relevance 0

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