INT236078

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (AGER, HLA-DMA) extracellular space (AGER) extracellular region (AGER)
intracellular (HLA-DMA) protein complex assembly (HLA-DMA) cytoplasm (AGER)
AGER (Homo sapiens)
HLA-DMA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 69 98.64 Very High Very High Very High
Diabetes Complications 8 86.24 High High
Renal Disease 20 60.08 Quite High
Disease 18 43.12 Quite Low
Ocular Toxicity (including Many Sub-types) 16 34.72 Quite Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Myocardial Infarction 7 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 6 5.00 Very Low Very Low Very Low
Albuminuria 4 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we could not test whether LTA, TNF and AGER polymorphisms are in linkage disequilibrium in type 1 diabetic patients as suggested by Laki et. al. who recently showed that the HLA 8.1 ancestral haplotype (8.1 AH) was strongly linked to the AGER -429T?
AGER Binding (linked) of HLA associated with diabetes mellitus
1) Confidence 0.08 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2429972 Disease Relevance 0.81 Pain Relevance 0

General Comments

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