INT236091

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 2.78
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il2) extracellular region (Il2)
Anatomy Link Frequency
T cells 8
spleen 2
Il2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 61 96.96 Very High Very High Very High
cytokine 175 93.80 High High
medulla 8 50.12 Quite High
Spinal cord 35 34.60 Quite Low
Bile 12 17.48 Low Low
anesthesia 15 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 21 98.72 Very High Very High Very High
INFLAMMATION 62 96.96 Very High Very High Very High
Disease 31 92.52 High High
Fever 6 84.80 Quite High
Infection 18 74.88 Quite High
Sprains And Strains 54 50.00 Quite Low
Asthma 6 7.92 Low Low
Motor Neuron Diseases 26 5.00 Very Low Very Low Very Low
Disease Progression 13 5.00 Very Low Very Low Very Low
Body Weight 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased IL-2 and IL-2 receptor transcription also implicates the activation of T cells.
Positive_regulation (Increased) of Transcription (transcription) of IL-2 in T cells
1) Confidence 0.44 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0.55 Pain Relevance 0.18
As shown in figure 2A, significant increases in IL-2 gene transcription were detected at day 7 and 11 with all dose groups and at day 11, IL-2 mRNA levels peaked at almost double the control.
Positive_regulation (increases) of Transcription (transcription) of IL-2 gene
2) Confidence 0.44 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0 Pain Relevance 0.12
Increased IL-2 and IL-2 receptor transcription also implicates the activation of T cells.
Positive_regulation (activation) of Transcription (transcription) of IL-2 in T cells
3) Confidence 0.32 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0.60 Pain Relevance 0.17
Increased IL-2 and IL-2 receptor transcription also implicates the activation of T cells.
Positive_regulation (Increased) of Transcription (transcription) of IL-2 in T cells
4) Confidence 0.32 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0.55 Pain Relevance 0.18
Increased IL-2 and IL-2 receptor transcription also implicates the activation of T cells.
Positive_regulation (Increased) of Transcription (transcription) of IL-2 in T cells
5) Confidence 0.32 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0.55 Pain Relevance 0.18
Also, via RT-PCR we detected a significant increase of IL-2 and IL-2 receptor gene transcription level after 7 days of oral administration of LcZhang.
Positive_regulation (increase) of Transcription (transcription) of IL-2
6) Confidence 0.29 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2596084 Disease Relevance 0.52 Pain Relevance 0.21
Although, there were no statistical differences in IL-2 mRNA and IL-10 m RNA expressions between G93A mice treated with different cell doses and control animals (Media, CsA, hTgn, C57), mice receiving 25×106 MNC hUCB cells tended towards decreased IL-2 mRNA and increased IL-10 mRNA expressions in the spleen.
Neg (no) Positive_regulation (differences) of Transcription (expressions) of IL-2 in spleen
7) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2429976 Disease Relevance 0 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox