INT236163

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Context Info
Confidence 0.64
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 6
Total Number 10
Disease Relevance 0.66
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmgcr) embryo development (Hmgcr)
Anatomy Link Frequency
CGR8 1
cones 1
spinal cord 1
epithelial cell 1
lungs 1
Hmgcr (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 42 100.00 Very High Very High Very High
amygdala 40 100.00 Very High Very High Very High
Spinal cord 20 100.00 Very High Very High Very High
anesthesia 19 96.24 Very High Very High Very High
isoflurane 10 95.04 Very High Very High Very High
imagery 55 91.60 High High
antagonist 6 59.64 Quite High
cytokine 41 53.04 Quite High
Inflammation 102 43.52 Quite Low
fibrosis 95 12.04 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 72 97.40 Very High Very High Very High
Apoptosis 32 49.76 Quite Low
INFLAMMATION 132 43.52 Quite Low
Pseudomonas Infection 90 33.68 Quite Low
Targeted Disruption 13 27.48 Quite Low
Pulmonary Disease 105 25.88 Quite Low
Obstructive Airway Disease 10 25.20 Quite Low
Body Weight 5 20.00 Low Low
Bacterial Respiratory Disease 5 12.32 Low Low
Cystic Fibrosis 95 12.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NV Jade was therefore chosen as the best dye for evaluation in longer term studies tracing longer fibers based on its better thermal stability compared with PTIR 326 (Figure 1), its comparable detection distances at similar concentrations compared with NV Red and NV Maroon in the 4 day neonatal murine spinal cord assay (Figure 3), and its good spectral segregation from longer wavelength dyes (Figure 4).
Localization (segregation) of NV Red in spinal cord associated with spinal cord
1) Confidence 0.64 Published 2007 Journal Immunological Investigations Section Body Doc Link PMC2430174 Disease Relevance 0 Pain Relevance 0.12
The Red and Pink module differentiating between amygdala and hippocampus, however, are not conserved in spinal cord and are therefore more likely to be amygdala or hippocampus specific.
Neg (not) Localization (conserved) of Red in amygdala associated with hippocampus, amygdala and spinal cord
2) Confidence 0.51 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2823687 Disease Relevance 0.66 Pain Relevance 0.61
We observed significant amount of PLGA-PEGPS341-NileRed particles in murine lungs by 24 hrs and observed its sustained release from days 1 to 11 given the short half-life of the nile red (Fig 4).
Localization (release) of PLGA-PEGPS341-NileRed in lungs
3) Confidence 0.36 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2954907 Disease Relevance 0 Pain Relevance 0.19
Nanoparticle samples were aliquoted and incubated at room temperature in triplicate for indicated time points and analyzed for nile red release.
Spec (analyzed) Localization (release) of red
4) Confidence 0.32 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2954907 Disease Relevance 0 Pain Relevance 0
Release kinetics of nile red from PLGA-PEG nanoparticles was quantified by recording absorption of released dye in resuspension buffer (PBS, 100 ?
Localization (Release) of red
5) Confidence 0.32 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2954907 Disease Relevance 0 Pain Relevance 0
We determined the in vitro efficacy of the nanoparticle system by evaluating the release kinetics of short-lived dye (30 mins), nile red, from PLGA-PEG nanoparticles by quantifying the absorption of released dye at 525 nm.
Localization (release) of red
6) Confidence 0.30 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2954907 Disease Relevance 0 Pain Relevance 0
We observed the cytosolic release of nile red in perinuclear space (Fig 5) that verifies the efficacy of our therapeutic vehicle for bronchial epithelial cell delivery.
Localization (release) of red in epithelial cell
7) Confidence 0.30 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2954907 Disease Relevance 0 Pain Relevance 0.14
The CGR8 ES cell line was transfected with the nuclear-localized red fluorescent protein (DsRed-Nuc) gene that is expressed under the cardiac ?
Localization (localized) of red in CGR8
8) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2483414 Disease Relevance 0 Pain Relevance 0.03
In Opn1mwR mice there is a substantial divergence in relative sensitivity of melanopsin, rods, and red cones between these two wavelengths (FigureĀ 1B).
Localization (sensitivity) of red in cones
9) Confidence 0.13 Published 2010 Journal Neuron Section Body Doc Link PMC2875410 Disease Relevance 0 Pain Relevance 0
As shown in Fig. 3Da,b,c, a robust intracellular fluorescence of NBD-PS (but not of NBD-PC) was co-localized, at least in part, with a lysosomal marker, Lyso-Tracker Red.
Localization (localized) of Red
10) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2634966 Disease Relevance 0 Pain Relevance 0.03

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