INT23630

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Context Info
Confidence 0.62
First Reported 1984
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.90
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (fut10) Golgi apparatus (fut10)
Anatomy Link Frequency
blood 1
fut10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 4 99.88 Very High Very High Very High
antagonist 2 88.96 High High
Inflammation 2 71.80 Quite High
cINOD 2 67.28 Quite High
anesthesia 1 62.00 Quite High
Neurotransmitter 1 48.48 Quite Low
Catecholamine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Arrhythmogenic Right Ventricular Dysplasia 2 99.04 Very High Very High Very High
Nephritis 1 92.72 High High
Bacterial Infection 2 92.52 High High
Renal Disease 3 83.04 Quite High
Injury 1 75.00 Quite High
INFLAMMATION 4 71.80 Quite High
Body Weight 1 53.84 Quite High
Heart Rate Under Development 2 51.44 Quite High
Shock 3 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This investigation examined the effects of two structurally dissimilar inhibitors of (Tx) synthetase on Salmonella enteritidis endotoxin (LPS) (15 mg/kg)-induced alterations in cardiac output and organ blood flow in Long-Evans rats.
Gene_expression (synthetase) of Tx in blood
1) Confidence 0.62 Published 1986 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2425166 Disease Relevance 0.22 Pain Relevance 0.06
Brevetoxin-B (GbTX-B), a cyclic polyether purified from the marine dinoflagellate Gymnodinium breve, produced positive inotropic and arrhythmogenic effects on isolated rat and guinea pig cardiac preparations at concentrations between 1.25 X 10(-8) and 1.87 X 10(-7) M.
Gene_expression (produced) of GbTX-B associated with arrhythmogenic right ventricular dysplasia
2) Confidence 0.30 Published 1984 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 6093288 Disease Relevance 0.15 Pain Relevance 0
The time course of TxB2 production as a function of unbound naproxen concentrations was described by a sigmoid Emax model.
Gene_expression (production) of TxB2
3) Confidence 0.18 Published 1995 Journal Exp. Gerontol. Section Abstract Doc Link 8557098 Disease Relevance 0 Pain Relevance 0
Tx gamma (50 ng) and fraction T2III1 (2.5 ng) produced a tetrodotoxin-sensitive increase in the frequency of miniature endplate potentials (m.e.p.p.) and a transitory reduction of the resting potential.
Gene_expression (produced) of Tx gamma associated with tetrodotoxin
4) Confidence 0.06 Published 1989 Journal Gen. Pharmacol. Section Abstract Doc Link 2714618 Disease Relevance 0 Pain Relevance 0.26
Dazmegrel, in doses sufficient to effectively block glomerular TxA2 synthesis, significantly increased 12-HETE and PGE2 synthesis without an effect on the synthesis of LTB4.
Gene_expression (synthesis) of TxA2
5) Confidence 0.01 Published 1999 Journal J. Lab. Clin. Med. Section Abstract Doc Link 10560941 Disease Relevance 0.53 Pain Relevance 0.22

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