INT236314

Context Info Confidence 0.00 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.50 Pain Relevance 0

extracellular space (CD14) extracellular region (CD14) plasma membrane (CD14)

Anatomy Link Frequency macrophages 1 monocytes 1 IGKV2D-38 (Homo sapiens) CD14 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 58 50.00 corticosteroid 14 5.00 cytokine 10 5.00 chemokine 4 5.00 Inflammatory mediators 2 5.00 aspirin 2 5.00 cINOD 2 5.00 Inflammatory stimuli 2 5.00

Disease Link Frequency Relevance Heat Urological Neuroanatomy 22 87.44 INFLAMMATION 64 50.00 Disease 16 5.00 Occupational Lung Diseases 12 5.00 Asthma 12 5.00 Pulmonary Disease 12 5.00 Injury 8 5.00 Hypersensitivity 4 5.00 Lung Injury 4 5.00 Adhesions 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Figure 3 shows the effect of 0.5 and 2 mg pretreatments with FP on O3-induced changes in the cell-surface markers CD11b, mCD14, CD64, CD16, HLA-DR, and CD86 on monocytes, macrophages, and DCs.

O3 Regulation (changes) of mCD14 in macrophages

1) Confidence 0.00 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2430237 Disease Relevance 0.25 Pain Relevance 0

Figure 3 shows the effect of 0.5 and 2 mg pretreatments with FP on O3-induced changes in the cell-surface markers CD11b, mCD14, CD64, CD16, HLA-DR, and CD86 on monocytes, macrophages, and DCs.

O3 Regulation (changes) of mCD14 in monocytes

2) Confidence 0.00 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2430237 Disease Relevance 0.25 Pain Relevance 0

General Comments

This test has worked.