INT236330

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Context Info
Confidence 0.59
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.55
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SFTPD) extracellular region (SFTPD) lysosome (SFTPD)
SFTPD (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 7 99.84 Very High Very High Very High
cytokine 5 98.76 Very High Very High Very High
rheumatoid arthritis 55 97.76 Very High Very High Very High
Inflammatory mediators 1 91.80 High High
chemokine 2 90.68 High High
Inflammation 45 87.28 High High
methotrexate 9 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 2 99.32 Very High Very High Very High
Rheumatoid Arthritis 55 97.76 Very High Very High Very High
Disease 31 92.04 High High
INFLAMMATION 45 91.40 High High
Injury 4 82.84 Quite High
Adhesions 1 45.92 Quite Low
Lung Injury 2 25.04 Quite Low
Apoptosis 2 17.20 Low Low
Nicotine Addiction 12 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Altered SP-D expression due to genotype abnormalities should be considered.
Regulation (Altered) of Gene_expression (expression) of SP-D associated with congenital anomalies
1) Confidence 0.59 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888186 Disease Relevance 1.08 Pain Relevance 0.34
We previously showed that intracellular SP-D mRNA and protein expression are very sensitive to corticosteroids, cAMP, and cytokine levels (Cao et al. 2004) and that SP-D in broncho-alveolar lavage fluid is subject to rapid break-down after O3 exposure of mice (Kierstein et al. 2006).
Regulation (sensitive) of Gene_expression (expression) of SP-D associated with corticosteroid and cytokine
2) Confidence 0.07 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2430237 Disease Relevance 0.47 Pain Relevance 0.32

General Comments

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