INT236359

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Agtr2) plasma membrane (Agtr2) transcription factor binding (Agtr2)
signal transducer activity (Agtr2)
Anatomy Link Frequency
juxtaglomerular cells 2
microglia 2
Agtr2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 38 92.80 High High
Hippocampus 3 92.40 High High
cINOD 5 58.68 Quite High
chemokine 20 5.00 Very Low Very Low Very Low
cerebral cortex 10 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 121 99.32 Very High Very High Very High
Disease Progression 2 95.28 Very High Very High Very High
Targeted Disruption 17 89.44 High High
Amyloid Plaque 7 77.20 Quite High
Gliosis 3 76.40 Quite High
Chronic Renal Failure 64 76.20 Quite High
Death 7 65.48 Quite High
Necrosis 3 51.52 Quite High
Cancer 3 51.16 Quite High
Alzheimer's Dementia 5 43.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Renin release can also be inhibited by a direct action of angiotensin II on the juxtaglomerular cells.
Negative_regulation (inhibited) of Positive_regulation (action) of angiotensin II in juxtaglomerular cells
1) Confidence 0.07 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.27 Pain Relevance 0
Activation of cultured microglia with toll-like receptor 2 (TLR2), TLR4, or TLR9 ligand markedly boosted ingestion of A?
Negative_regulation (boosted) of Positive_regulation (Activation) of receptor 2 in microglia
2) Confidence 0.03 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2430555 Disease Relevance 1.34 Pain Relevance 0.15

General Comments

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