INT236364

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CD40LG, IL6) extracellular region (CD40LG, IL6) aging (IL6)
plasma membrane (CD40LG)
Anatomy Link Frequency
endothelial cells 2
CD40LG (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 3 98.00 Very High Very High Very High
Arthritis 82 97.36 Very High Very High Very High
Inflammatory mediators 1 93.52 High High
cytokine 44 74.48 Quite High
Inflammation 17 68.88 Quite High
rheumatoid arthritis 11 67.28 Quite High
methotrexate 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 97.68 Very High Very High Very High
Juvenile Chronic Polyarthritis 73 97.36 Very High Very High Very High
Leukemia 1 83.72 Quite High
Rheumatoid Arthritis 11 67.28 Quite High
Experimental Arthritis 1 53.80 Quite High
Syndrome 2 32.16 Quite Low
Systemic Sclerosis 2 31.24 Quite Low
Inflammatory Bowel Disease 3 30.44 Quite Low
Systemic Lupus Erythematosus 5 30.08 Quite Low
Autoimmune Disease 3 29.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that sCD154 has the potential to activate endothelial cells in vitro, and increase production of IL6 [14].
sCD154 Positive_regulation (increase) of Gene_expression (production) of IL6 in endothelial cells
1) Confidence 0.25 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2430568 Disease Relevance 1.37 Pain Relevance 0.72

General Comments

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