INT236480

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SNRPB) nucleoplasm (SNRPB) mRNA processing (SNRPB)
nucleus (SNRPB) cytoplasm (SNRPB)
Anatomy Link Frequency
lamina 2
SNRPB (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 3 79.12 Quite High
cytokine 4 51.52 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Blister 14 99.56 Very High Very High Very High
Junctional Epidermolysis Bullosa 3 72.00 Quite High
Bullous Skin Disease 1 57.60 Quite High
Injury 16 55.52 Quite High
Death 13 36.28 Quite Low
Apoptosis 12 25.96 Quite Low
Lung Injury 3 11.04 Low Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Cognitive Disorder 18 5.00 Very Low Very Low Very Low
Necrosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
where SM(?
Positive_regulation (where) of Gene_expression (where) of SM
1) Confidence 0.13 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
BPA immunoreactivity is diminished in SM-exposed guinea pig skin.81 BP180 is a transmembrane protein with a collagenous carboxyl-terminal extracellular domain.82 Immunoelectron microscopic studies demonstrated that the C-terminal part of BP180 actually reaches into the lamina densa.83 Immunhistochemical studies revealed that BP180 was present in both the epidermis (blister roof) and dermis (blister ground) of mice skin following SM exposure.80 This supports in part the findings of earlier studies that described intact hemidesmosomal components and attached anchoring filaments to be forming the roof of the blister and the lamina densa its base.76
Positive_regulation (following) of Gene_expression (exposure.80) of SM in lamina associated with blister
2) Confidence 0.02 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0.79 Pain Relevance 0.10

General Comments

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