INT236481

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PARP1) nuclear envelope (PARP1) transferase activity, transferring glycosyl groups (PARP1)
intracellular (PARP1) DNA binding (PARP1) nucleolus (PARP1)
PARP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 1 76.72 Quite High
cytokine 4 40.16 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 13 98.72 Very High Very High Very High
Apoptosis 12 98.00 Very High Very High Very High
Dna Damage 1 62.84 Quite High
Necrosis 8 54.68 Quite High
Ataxia 1 41.08 Quite Low
Injury 16 36.24 Quite Low
Blister 14 33.36 Quite Low
Bullous Skin Disease 1 28.96 Quite Low
Junctional Epidermolysis Bullosa 3 13.76 Low Low
Lung Injury 3 8.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PARP inhibition also blocks DNA repair59 and thereby promoting cell death by apoptosis.73
Negative_regulation (blocks) of Negative_regulation (inhibition) of PARP associated with apoptosis and death
1) Confidence 0.15 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0.95 Pain Relevance 0.04

General Comments

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