INT236516

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.23
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cacna1f)
Cacna1f (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 14 28.36 Quite Low
Neurotransmitter 23 28.08 Quite Low
addiction 9 19.08 Low Low
Calcium channel 12 5.00 Very Low Very Low Very Low
Action potential 9 5.00 Very Low Very Low Very Low
long-term potentiation 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rod Or Cone Dystrophy 5 84.48 Quite High
Night Blindness 35 81.16 Quite High
Disease 42 65.92 Quite High
Channelopathies 51 50.00 Quite Low
Hypokalemic Periodic Paralysis 87 5.00 Very Low Very Low Very Low
Dystonia 30 5.00 Very Low Very Low Very Low
Malignant Hyperthermia 24 5.00 Very Low Very Low Very Low
Targeted Disruption 22 5.00 Very Low Very Low Very Low
Syndrome 18 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PD98059, a specific inhibitor of MAPKK, did not have a differential effect on the biophysical properties of either Cav1.4nob2 or Cav1.4wt, suggesting that the difference in biophysical properties of these channels is not due to a difference in phosphorylation within these 20 amino acids.
Regulation (effect) of Cav1.4nob2
1) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2432030 Disease Relevance 0 Pain Relevance 0
PD98059, a specific inhibitor of MAPKK, did not have a differential effect on the biophysical properties of either Cav1.4nob2 or Cav1.4wt, suggesting that the difference in biophysical properties of these channels is not due to a difference in phosphorylation within these 20 amino acids.
Regulation (effect) of Cav1.4wt
2) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2432030 Disease Relevance 0 Pain Relevance 0
A truncating CSNB2 mutation reveals an intrinsic gating modulator in Cav1.4
Regulation (modulator) of Cav1.4
3) Confidence 0.37 Published 2010 Journal Pflugers Arch Section Body Doc Link PMC2883925 Disease Relevance 0.23 Pain Relevance 0
1 subunit mutations have provided valuable insight into the molecular mechanisms underlying the regulation not only of Cav1.4 but also Cav1.3 LTCCs.
Regulation (regulation) of Cav1.4
4) Confidence 0.37 Published 2010 Journal Pflugers Arch Section Body Doc Link PMC2883925 Disease Relevance 0 Pain Relevance 0
The possibility that the mutations affect Cav1.4 ?
Regulation (affect) of Cav1.4
5) Confidence 0.37 Published 2010 Journal Pflugers Arch Section Body Doc Link PMC2883925 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox