INT236527

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.45
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cacna2d1)
Anatomy Link Frequency
sciatic nerve 1
Cacna2d1 (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 2 99.98 Very High Very High Very High
Calcium channel 6 91.76 High High
Pain 66 63.00 Quite High
allodynia 15 61.68 Quite High
Neuropeptide 1 56.00 Quite High
Eae 26 40.56 Quite Low
dorsal root ganglion 18 7.68 Low Low
Brush evoked pain 21 5.00 Very Low Very Low Very Low
Neuropathic pain 20 5.00 Very Low Very Low Very Low
Spontaneous pain 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 130 99.44 Very High Very High Very High
Nervous System Injury 19 65.20 Quite High
Pain 71 63.00 Quite High
Neuropathic Pain 62 61.68 Quite High
Ganglion Cysts 21 39.44 Quite Low
Neuroma 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Night Blindness 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Seven of the eight are known to be significantly regulated in L5DRGs in rats following sciatic nerve transection (Gal, Pacap, Cchl2a, Sprr1a, C-Jun, Trpv1 and Scn11a) while one is not regulated (Mmpcp1; [2]).
Localization (transection) of Cchl2a in sciatic nerve associated with sciatic nerve
1) Confidence 0.41 Published 2009 Journal Mol Pain Section Body Doc Link PMC2649910 Disease Relevance 0.35 Pain Relevance 0.26
Cacna1fnob2 and Cacna1fwt optokinetic responses (OKR) are similar
Localization (responses) of Cacna1fnob2
2) Confidence 0.27 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2432030 Disease Relevance 0.10 Pain Relevance 0.05

General Comments

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