INT236692

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cdk4) cytosol (Cdk4) signal transduction (Cdk4)
nucleolus (Cdk4) nucleus (Cdk4) cell cycle (Cdk4)
Anatomy Link Frequency
muscle 1
Cdk4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 9 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 1 97.36 Very High Very High Very High
Cancer 50 96.16 Very High Very High Very High
Apoptosis 31 90.08 High High
Hyperplasia 2 87.20 High High
Breast Cancer 4 77.60 Quite High
Myotonic Dystrophy 8 50.00 Quite Low
Colon Cancer 22 44.64 Quite Low
Squamous Cell Carcinoma 1 40.24 Quite Low
Stomach Cancer 1 22.16 Low Low
Pancreatic Cancer 1 15.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
phosphorylation, such as cyclin D1, CDK4, CDK6, and CDK2 [158]. pRB is a
Phosphorylation (phosphorylation) of CDK4
1) Confidence 0.35 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.82 Pain Relevance 0
Cyclin D3-cdk4-mediated phosphorylation of CUG-BP1 increased formation of the translational CUG-BP1-eIF2 complexes during normal muscle differentiation.
Phosphorylation (phosphorylation) of cdk4 in muscle
2) Confidence 0.12 Published 2008 Journal Current Genomics Section Body Doc Link PMC2694559 Disease Relevance 0 Pain Relevance 0

General Comments

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