INT236705

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cdk2) cytoplasm (Cdk2) cytosol (Cdk2)
mitosis (Cdk2) nucleus (Cdk2) cytoskeleton (Cdk2)
Cdk2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 9 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 1 98.64 Very High Very High Very High
Cancer 50 97.44 Very High Very High Very High
Apoptosis 31 90.08 High High
Hyperplasia 2 87.20 High High
Machado-joseph Disease 12 83.56 Quite High
Toxicity 14 82.88 Quite High
Disease 25 80.40 Quite High
Breast Cancer 4 77.60 Quite High
Targeted Disruption 26 57.68 Quite High
Colon Cancer 22 44.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
phosphorylation, such as cyclin D1, CDK4, CDK6, and CDK2 [158]. pRB is a
Phosphorylation (phosphorylation) of CDK2
1) Confidence 0.31 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.82 Pain Relevance 0
Recent studies implicate the third UIM in casein kinase 2-dependent ataxin-3 phosphorylation [39], a modification that influences nucleocytoplasmic shuttling and intranuclear aggregation of ataxin-3.
Phosphorylation (phosphorylation) of kinase 2-dependent
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965175 Disease Relevance 0.57 Pain Relevance 0

General Comments

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