INT236707

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.97
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) nucleus (Ppara) DNA binding (Ppara)
lipid metabolic process (Ppara)
Ppara (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 183 100.00 Very High Very High Very High
cytokine 20 98.00 Very High Very High Very High
agonist 67 96.28 Very High Very High Very High
COX2 46 69.92 Quite High
psoriasis 6 31.04 Quite Low
cINOD 10 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 190 100.00 Very High Very High Very High
Repression 11 100.00 Very High Very High Very High
Sprains And Strains 32 99.60 Very High Very High Very High
Apoptosis 53 98.88 Very High Very High Very High
Colon Cancer 46 90.68 High High
Injury 28 83.92 Quite High
Adhesions 4 82.72 Quite High
Cancer 205 80.72 Quite High
Liver Cancer 5 77.60 Quite High
Hepatomegaly 8 75.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B

signaling resulted in the suppression of PPAR?

Regulation (resulted) of Negative_regulation (suppression) of PPAR
1) Confidence 0.41 Published 2008 Journal PPAR Research Section Body Doc Link PMC2606065 Disease Relevance 1.23 Pain Relevance 0.40
Thus the expression levels of PPAR?
Regulation (Thus) of Negative_regulation (levels) of PPAR
2) Confidence 0.40 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.10 Pain Relevance 0
With regard to TRI metabolism, urinary TCA levels in Ppar?
Regulation (regard) of Negative_regulation (levels) of Ppar
3) Confidence 0.38 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.44 Pain Relevance 0.03
Because hepatic ALDH2 protein expression was inhibited by TRI exposure in all three mouse strains, it is an unlikely cause of the decreased urinary levels of TCA in Ppar?
Regulation (cause) of Negative_regulation (decreased) of Ppar associated with sprains and strains
4) Confidence 0.38 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.19 Pain Relevance 0.05
Using reporter assays, mir-122 was shown to down-regulate PPAR?
Regulation (regulate) of Negative_regulation (down) of PPAR
5) Confidence 0.27 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943104 Disease Relevance 0 Pain Relevance 0.07
-1

signaling is responsible for the repression of inflammatory-induced PPAR?

Regulation (responsible) of Negative_regulation (repression) of PPAR associated with inflammation and repression
6) Confidence 0.25 Published 2008 Journal PPAR Research Section Body Doc Link PMC2606065 Disease Relevance 1.01 Pain Relevance 0.25

General Comments

This test has worked.

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