INT236718

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (KLK15) extracellular region (KLK15)
Anatomy Link Frequency
hepatocytes 1
KLK15 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 18 96.16 Very High Very High Very High
Inflammation 4 11.72 Low Low
cINOD 16 5.00 Very Low Very Low Very Low
COX2 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Liver Cancer 6 85.04 High High
Solid Tumor 2 72.00 Quite High
Apoptosis 62 70.72 Quite High
Disorder Of Lipid Metabolism 8 60.24 Quite High
Repression 8 53.20 Quite High
Dyslipidemia /

Combined Dyslipidemia

6 35.76 Quite Low
Cancer 100 31.92 Quite Low
Syndrome 2 27.72 Quite Low
Diabetes Mellitus 10 26.80 Quite Low
Stress 4 19.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
upregulates the expression levels of ACO via PPRE in the promoter region [42, 43].
Positive_regulation (upregulates) of ACO
1) Confidence 0.03 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.22 Pain Relevance 0
human liver cell lines and primary hepatocytes did not induce ACO mRNA by
Neg (not) Positive_regulation (induce) of ACO in hepatocytes
2) Confidence 0.02 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.12 Pain Relevance 0.05

General Comments

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