INT236720

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.80
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ctnnd2, Tcf4) cell differentiation (Tcf4) cell adhesion (Ctnnd2)
DNA binding (Tcf4)
Anatomy Link Frequency
T-cell 1
Ctnnd2 (Mus musculus)
Tcf4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 46.12 Quite Low
Inflammation 15 45.72 Quite Low
cINOD 16 38.56 Quite Low
aspirin 2 34.16 Quite Low
agonist 18 5.00 Very Low Very Low Very Low
COX2 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 109 98.52 Very High Very High Very High
Colon Cancer 47 94.40 High High
Familial Adenomatous Polyposis 16 94.08 High High
Adenocarcinoma 3 91.88 High High
Adenoma 41 90.68 High High
Colorectal Cancer 20 85.92 High High
Aberrant Crypt Foci 5 53.72 Quite High
Disease 9 52.12 Quite High
Colitis 12 50.72 Quite High
Repression 8 50.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin itself leading to nuclear translocation and binding to TCF4 (T-cell Factor 4).
catenin Binding (binding) of TCF4 in T-cell
1) Confidence 0.24 Published 2010 Journal Journal of Carcinogenesis Section Body Doc Link PMC2862504 Disease Relevance 0.74 Pain Relevance 0
-catenin-TCF-4 transcription complex
catenin Binding (complex) of TCF-4
2) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 0.99 Pain Relevance 0
-catenin-TCF-4 transcription complex
catenin Binding (complex) of TCF-4
3) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2435221 Disease Relevance 1.07 Pain Relevance 0

General Comments

This test has worked.

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