INT236729

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.39
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cortex 2
CRS (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 22 85.76 High High
Hippocampus 30 85.36 High High
antagonist 28 74.76 Quite High
medulla 21 47.72 Quite Low
agonist 16 44.48 Quite Low
long-term potentiation 9 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
interneuron 6 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
Buprenorphine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 8 94.96 High High
Phobia 1 90.48 High High
Amnesia 1 78.80 Quite High
Gliosis 6 71.96 Quite High
Overdose 3 54.80 Quite High
Depression 12 5.00 Very Low Very Low Very Low
Aging 11 5.00 Very Low Very Low Very Low
Cognitive Disorder 10 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Frailty 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When made after conditioning has been established, similar interventions impair or prevent the expression of CRs [10], [12], [13], and see [14], [15] for reviews.
Negative_regulation (prevent) of Gene_expression (expression) of CRs
1) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
When made after conditioning has been established, similar interventions impair or prevent the expression of CRs [10], [12], [13], and see [14], [15] for reviews.
Negative_regulation (impair) of Gene_expression (expression) of CRs
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0 Pain Relevance 0
A cortical cannula placement was considered on-target only if both muscimol and CNQX infusions produced a suitably rapid and profound abolition of CRs during Phase 5 Performance Testing (demonstrating that muscimol was effective at inactivating cortex within the temporal window vital for consolidation, but without significantly spreading to nuclei).
Negative_regulation (abolition) of Gene_expression (produced) of CRs in cortex
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912226 Disease Relevance 0.13 Pain Relevance 0
CRs can also be extinguished, and this is in fact why it is widely used in the
Negative_regulation (is) of Gene_expression (extinguished) of CRs
4) Confidence 0.07 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2435227 Disease Relevance 0.26 Pain Relevance 0.15

General Comments

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