INT236915

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.51
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Map2k1) cytoplasm (Map2k1) cytosol (Map2k1)
cell proliferation (Map2k1) mitosis (Map2k1) cell motility (Map2k1)
Map2k1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 74 97.44 Very High Very High Very High
Arthritis 10 90.60 High High
cytokine 6 85.84 High High
Inflammation 15 85.44 High High
spinal inflammation 10 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
COX2 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
cOX1 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 74 97.44 Very High Very High Very High
Arthritis 12 90.60 High High
INFLAMMATION 15 85.44 High High
Ductal Carcinoma 1 84.20 Quite High
Breast Cancer 5 80.36 Quite High
Cancer 71 70.20 Quite High
Carcinoma 5 69.36 Quite High
Metaplasia 1 66.88 Quite High
Stomach Cancer 1 62.08 Quite High
Stress 5 58.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test whether autoantibodies to BRAF may influence BRAF activity as a kinase, we developed a phosphorylation assay using BRAF, MEK1 (its major substrate) and autoantibodies to BRAF purified from RA patients' sera.
MEK1 Binding (using) of associated with rheumatoid arthritis
1) Confidence 0.15 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991030 Disease Relevance 0.79 Pain Relevance 0.49
with MEK1 through association of
MEK1 Binding (association) of
2) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2440494 Disease Relevance 0.72 Pain Relevance 0

General Comments

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