INT236946

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr5) plasma membrane (Cxcr5) signal transducer activity (Cxcr5)
Anatomy Link Frequency
B cells 1
Cxcr5 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 1 73.84 Quite High
Chronic pancreatitis 37 57.80 Quite High
Inflammation 21 50.68 Quite High
fibrosis 9 14.88 Low Low
Bile 6 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 3 97.20 Very High Very High Very High
Inflammatory Bowel Disease 9 87.88 High High
Syndrome 4 86.96 High High
Disease 33 76.48 Quite High
Graves' Ophthalmopathy 1 76.12 Quite High
Rheumatoid Arthritis 1 73.84 Quite High
Pancreatitis 54 61.20 Quite High
Primary Sclerosing Cholangitis 30 60.00 Quite High
INFLAMMATION 20 50.68 Quite High
Biliary Tract Disease 1 26.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In analogy to mechanisms postulated in other autoimmune disorders [23], the formation of ectopic lymph follicles with germinal centers where B cells undergo maturation and activation, driven by the CXCL13-CXCR5 interaction, would therefore be essential for the pathogenesis of AIPC.
CXCR5 Binding (interaction) of in B cells associated with autoimmune disease
1) Confidence 0.41 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 1.13 Pain Relevance 0.17

General Comments

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