INT236959

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 5.77
Pain Relevance 2.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PDZD2) cell adhesion (PDZD2) endoplasmic reticulum (PDZD2)
nucleus (PDZD2) cytoplasm (PDZD2)
Anatomy Link Frequency
macrophages 1
plasma cells 1
head 1
T lymphocytes 1
PDZD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 222 100.00 Very High Very High Very High
Inflammation 126 98.48 Very High Very High Very High
fibrosis 54 91.52 High High
Inflammatory response 6 89.88 High High
addiction 5 89.28 High High
chemokine 6 82.88 Quite High
antagonist 1 51.76 Quite High
rheumatoid arthritis 6 15.92 Low Low
Arthritis 6 9.48 Low Low
Bile 36 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 324 100.00 Very High Very High Very High
Prostate Cancer 27 100.00 Very High Very High Very High
Cancer 18 100.00 Very High Very High Very High
Pancreatic Cancer 18 99.16 Very High Very High Very High
INFLAMMATION 120 98.48 Very High Very High Very High
Primary Sclerosing Cholangitis 180 98.04 Very High Very High Very High
Disease 198 94.72 High High
Malignant Neoplastic Disease 12 94.40 High High
Fibrosis 48 91.52 High High
Epstein-barr Virus 6 80.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIPC's increased proliferation and PSA secretion in the absence of androgen suggests a failure in the regulation of androgen receptor activation.
Localization (secretion) of AIPC associated with prostate cancer
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0.34 Pain Relevance 0.07
AIPC was localized in the pancreatic head in 94% of the patients.
Localization (localized) of AIPC in head
2) Confidence 0.08 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2440515 Disease Relevance 1.01 Pain Relevance 0.38
In order to define distinct and discriminative features of AIPC, the number and distribution of B and T lymphocytes, macrophages and plasma cells, including the subclass of IgG4-positive plasma cells, were analyzed.
Localization (features) of AIPC in plasma cells
3) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 0.61 Pain Relevance 0.24
SMA in AIPC compared to CP may account for the radiological and macroscopic tumor-like appearance of AIPC.
Localization (appearance) of AIPC associated with cancer and chronic pancreatitis
4) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 1.27 Pain Relevance 0.46
SMA in AIPC compared to CP may account for the radiological and macroscopic tumor-like appearance of AIPC.
Localization (appearance) of AIPC associated with cancer and chronic pancreatitis
5) Confidence 0.07 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 1.30 Pain Relevance 0.47
In order to define distinct and discriminative features of AIPC, the number and distribution of B and T lymphocytes, macrophages and plasma cells, including the subclass of IgG4-positive plasma cells, were analyzed.
Localization (features) of AIPC in macrophages
6) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 0.61 Pain Relevance 0.24
In order to define distinct and discriminative features of AIPC, the number and distribution of B and T lymphocytes, macrophages and plasma cells, including the subclass of IgG4-positive plasma cells, were analyzed.
Localization (features) of AIPC in T lymphocytes
7) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 0.61 Pain Relevance 0.24

General Comments

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