INT236960

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PDZD2) cell adhesion (PDZD2) endoplasmic reticulum (PDZD2)
nucleus (PDZD2) cytoplasm (PDZD2)
PDZD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 5 89.28 High High
Chronic pancreatitis 37 89.12 High High
Inflammation 21 82.36 Quite High
antagonist 1 50.32 Quite High
fibrosis 9 10.52 Low Low
Bile 6 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 27 100.00 Very High Very High Very High
Disease 33 92.08 High High
Pancreatitis 54 89.12 High High
Cirrhosis 5 85.64 High High
Primary Sclerosing Cholangitis 30 84.64 Quite High
INFLAMMATION 20 82.36 Quite High
Hypersensitivity 1 75.68 Quite High
Obesity 1 74.24 Quite High
Metastasis 2 32.92 Quite Low
Cancer 13 19.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIPC's increased proliferation and PSA secretion in the absence of androgen suggests a failure in the regulation of androgen receptor activation.
Positive_regulation (increased) of Gene_expression (proliferation) of AIPC associated with prostate cancer
1) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0.34 Pain Relevance 0.07
To confirm the overexpression of CXCR5 and CXCL13 in AIPC, real-time quantitative PCR was additionally performed.
Positive_regulation (overexpression) of Gene_expression (overexpression) of AIPC
2) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440515 Disease Relevance 1.03 Pain Relevance 0.46

General Comments

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