INT237158

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Tnf) signal transduction (Tnf) extracellular space (Tnf)
extracellular region (Tnf) plasma membrane (Tnf) intracellular (Tnf)
Anatomy Link Frequency
T cell 2
Tnf (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 42 97.28 Very High Very High Very High
Neuropeptide 26 95.92 Very High Very High Very High
cytokine 30 93.28 High High
Central nervous system 16 86.52 High High
Catecholamine 1 63.12 Quite High
Multiple sclerosis 6 45.84 Quite Low
adenocard 1 5.08 Very Low Very Low Very Low
Crohn's disease 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 20 99.36 Very High Very High Very High
INFLAMMATION 33 97.28 Very High Very High Very High
Disease 14 93.28 High High
Apoptosis 54 90.32 High High
Autoimmune Disease 9 89.72 High High
Colitis 17 88.24 High High
Mucositis 10 85.68 High High
Increased Venous Pressure Under Development 2 72.72 Quite High
Hypoxia 3 68.92 Quite High
Recurrence 1 49.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Th1 to Th2 shift, and the suppression of TNF alpha [14] has been established in
Negative_regulation (established) of Negative_regulation (suppression) of TNF alpha
1) Confidence 0.13 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2643053 Disease Relevance 0.42 Pain Relevance 0.43
Providing further evidence for its important role in regulating T cell function, galectin-4 blockade by antisense oligonucleotides reduced TNF-alpha inhibitor induced T cell death.
Negative_regulation (reduced) of Negative_regulation (inhibitor) of TNF-alpha in T cell associated with death
2) Confidence 0.05 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2440804 Disease Relevance 0.95 Pain Relevance 0.31

General Comments

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