INT237189

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LGALS4) cell adhesion (LGALS4) plasma membrane (LGALS4)
Anatomy Link Frequency
T cells 2
LGALS4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Adalimumab 4 93.48 High High
Inflammation 74 71.04 Quite High
cytokine 56 55.88 Quite High
addiction 2 38.24 Quite Low
Crohn's disease 8 21.32 Low Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 34 74.72 Quite High
INFLAMMATION 54 71.04 Quite High
Apoptosis 108 65.64 Quite High
Inflammatory Bowel Disease 36 62.36 Quite High
Disease 18 21.32 Low Low
Necrosis 6 19.20 Low Low
Cancer 4 18.84 Low Low
Mucositis 20 11.56 Low Low
Death 40 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following isolation of total RNA with RNA Bee, the efficacy of the specific siRNA to downregulate Gal-4 mRNA expression was determined by a TaqMan real-time PCR on a MxPro 3000 (Stratagene, CA) and quantified with Sybr®Green (Applied Biosystems).
Negative_regulation (downregulate) of Transcription (expression) of Gal-4
1) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0 Pain Relevance 0.05
Accordingly, Gal-4 mRNA expression in T cells was weak, but detectable (Fig. 1B) using GAPDH as a house-keeping gene.
Negative_regulation (detectable) of Transcription (expression) of Gal-4 in T cells
2) Confidence 0.38 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0.51 Pain Relevance 0.15

General Comments

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