INT237207

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.90
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LGALS4) cell adhesion (LGALS4) nucleus (Ik)
plasma membrane (LGALS4)
Anatomy Link Frequency
T cells 4
LGALS4 (Homo sapiens)
Ik (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 140 100.00 Very High Very High Very High
Inflammation 185 98.84 Very High Very High Very High
Inflammatory response 5 18.32 Low Low
Crohn's disease 20 5.00 Very Low Very Low Very Low
Adalimumab 10 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
abdominal pain 5 5.00 Very Low Very Low Very Low
addiction 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 135 98.84 Very High Very High Very High
Adhesions 5 94.52 High High
Colitis 85 87.36 High High
Mucositis 50 74.56 Quite High
Inflammatory Bowel Disease 90 69.08 Quite High
Apoptosis 270 66.08 Quite High
Urological Neuroanatomy 20 38.68 Quite Low
Disease 45 35.00 Quite Low
Body Weight 5 21.12 Low Low
Weight Loss 5 11.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We went on to determine the effect of Gal-4 on T cell cytokine secretion.


Gal-4 Spec (determine) Regulation (effect) of Localization (secretion) of cytokine in T cell associated with cytokine
1) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0 Pain Relevance 0.19
Next, we investigated the effect of Gal-4 on the cytokine secretion profile of CD2-stimulated LPT.
Gal-4 Spec (investigated) Regulation (effect) of Localization (secretion) of cytokine associated with cytokine
2) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0 Pain Relevance 0.18
Modulation of cytokine secretion in stimulated PBT and LPT by Gal-4
Gal-4 Regulation (Modulation) of Localization (secretion) of cytokine associated with cytokine
3) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0 Pain Relevance 0.19
Thus, to complete the picture, we measured the ability of Gal-4 to modulate cytokine secretion in this model of intestinal inflammation.


Gal-4 Regulation (modulate) of Localization (secretion) of cytokine associated with inflammation and cytokine
4) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0.90 Pain Relevance 0.48
Having demonstrated that Gal-4 substantially inhibits PBT cell cycling, we were interested in whether Gal-4 modulate cytokine release patterns in T cells.
Gal-4 Spec (whether) Regulation (modulate) of Localization (release) of cytokine in T cells associated with cytokine
5) Confidence 0.00 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440804 Disease Relevance 0 Pain Relevance 0.19

General Comments

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