INT237227
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Instillation of siRNA/cationic liposomes targeting polo-like kinase-1 or PLK-1, a biomarker of poor prognosis in a murine orthotopic bladder cancer model, resulted in significant inhibition of PLK-1 expression and lowering the PLK-1 protein level in bladder tissues, in a time- and dose-dependent manner (150).Another emerging experimental approach, still in preclinical evaluation, is using chemosensitizer to enhance the activity of agents with demonstrated clinical benefits. | |||||||||||||||
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