INT23724

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Context Info
Confidence 0.45
First Reported 1986
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nkx6-2) nucleus (Nkx6-2) DNA binding (Nkx6-2)
Anatomy Link Frequency
neurons 1
muscles 1
nerves 1
Nkx6-2 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 3 94.08 High High
Glutamate 3 92.88 High High
Action potential 4 84.08 Quite High
sodium channel 4 75.00 Quite High
tetrodotoxin 3 33.36 Quite Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 1 87.04 High High
Vomiting 1 86.36 High High
Sialorrhea 1 85.96 High High
Poisoning 2 80.72 Quite High
Neuroblastoma 2 71.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of geographutoxin II (GTX II), a novel polypeptide toxin isolated from the marine snail Conus geographus, on nerves and muscles were studied by current clamp and voltage clamp techniques.
Regulation (effects) of GTX in muscles
1) Confidence 0.45 Published 1986 Journal Pflugers Arch. Section Abstract Doc Link 2428010 Disease Relevance 0.07 Pain Relevance 0.12
In the present study, we determined the effects of GTX III on synaptic transmission in VMH neurons.
Spec (determined) Regulation (effects) of GTX in neurons
2) Confidence 0.21 Published 2010 Journal Neurotoxicology Section Abstract Doc Link 20038438 Disease Relevance 0.34 Pain Relevance 0.17
The effects of geographutoxin II (GTX II), a novel polypeptide toxin isolated from the marine snail Conus geographus, on nerves and muscles were studied by current clamp and voltage clamp techniques.
Regulation (effects) of GTX in nerves
3) Confidence 0.15 Published 1986 Journal Pflugers Arch. Section Abstract Doc Link 2428010 Disease Relevance 0.07 Pain Relevance 0.12

General Comments

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