INT237286

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prep) peptidase activity (Prep) mitochondrion (Dlat)
nucleus (Prep) transferase activity, transferring acyl groups (Dlat) cytoplasm (Prep)
Anatomy Link Frequency
PeVN 1
gonadal 1
Dlat (Rattus norvegicus)
Prep (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 471 100.00 Very High Very High Very High
gABA 3 49.20 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 6 5.00 Very Low Very Low Very Low
Overdose 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, our data suggest that in the female rat E2 and P act synergistically to affect SOM cell activity in the PeVN.



E2 Regulation (affect) of PeVN associated with somatostatin
1) Confidence 0.01 Published 2008 Journal Exp Brain Res Section Body Doc Link PMC2441535 Disease Relevance 0 Pain Relevance 0.41
Neither the number of SOM-ir cells, nor the total SOM-ir area in the PeVN was affected by E2 or P treatment alone.
E2 Neg (Neither) Regulation (affected) of PeVN in PeVN associated with somatostatin
2) Confidence 0.01 Published 2008 Journal Exp Brain Res Section Abstract Doc Link PMC2441535 Disease Relevance 0 Pain Relevance 0.62
E2 and P may act synergistically to affect SOM peptide in the PeVN, and the combination of both gonadal hormones may thus be essential for the generation of the typical feminine hypothalamic SOM release pattern.
E2 Regulation (affect) of PeVN in gonadal associated with somatostatin
3) Confidence 0.01 Published 2008 Journal Exp Brain Res Section Body Doc Link PMC2441535 Disease Relevance 0 Pain Relevance 0.54

General Comments

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