INT237325

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.09
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) extracellular region (Il6) nucleus (Ik)
Anatomy Link Frequency
adipocytes 2
T cells 2
Il6 (Mus musculus)
Ik (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 83 100.00 Very High Very High Very High
Inflammation 55 85.92 High High
chemokine 6 84.56 Quite High
Inflammatory mediators 5 55.92 Quite High
Inflammatory response 6 46.04 Quite Low
fibrosis 3 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 123 99.84 Very High Very High Very High
INFLAMMATION 67 85.92 High High
Hypersensitivity 24 76.80 Quite High
Hyperplasia 4 74.76 Quite High
Eosinophilia 8 73.40 Quite High
Asthma 104 70.56 Quite High
Necrosis 2 51.04 Quite High
Cancer 3 50.68 Quite High
Adhesions 2 50.28 Quite High
Diabetes Mellitus 6 20.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of this cytokine by TH17 cells depends on the signal transducer of activated T cells 3 (STAT-3) and is strongly induced by IL-6 [104].
IL-6 Positive_regulation (induced) of Gene_expression (expression) of cytokine in T cells associated with cytokine
1) Confidence 0.00 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.49 Pain Relevance 0.30
and IL-6, are known to stimulate cytokine expression in adipocytes [13-15] and establish a paracrine loop between these two cell types [16].
IL-6 Positive_regulation (stimulate) of Gene_expression (expression) of cytokine in adipocytes associated with obesity and cytokine
2) Confidence 0.00 Published 2008 Journal Nutr Metab (Lond) Section Body Doc Link PMC2441623 Disease Relevance 1.60 Pain Relevance 0.42

General Comments

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